Both are part of the twenty-one diseases classified as Neglected Tropical Diseases (NTDs) by the World Health Organization However, while buruli ulcer is a bacterial infection, Chagas disease is caused by protozoa.
Further, the former manifests as extensive ulceration on the skin of the upper and lower limbs, while the latter affect internal organs (eg, the heart and CNS) with prolonged asymptomatic period.
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